Many women experience PMS-like symptoms during pregnancy, particularly during the early weeks of pregnancy. Fatigue is extremely common during early pregnancy, and energy levels may remain low until the second trimester. Pregnant women often feel bloated and may have mild pelvic cramps. Headaches are also common. Breast tenderness or pain may also be experienced as hormones act on the breasts to prepare them for milk production and secretion. Some women also develop acne during pregnancy. PMS-like symptoms that are probably the most difficult for pregnant women to deal with are depression, anxiety, irritability, and mood swings.

The majority of medications to relieve these PMS-like symptoms are not advised during pregnancy. This can make it difficult for a woman who is experiencing moderate to severe symptoms in addition to the other changes she is dealing with. Getting adequate rest, including about 10 hours of sleep each night, is important for pregnant women and can help relieve fatigue. Wearing loose-fitting clothes and getting adequate exercise can minimize a bloated feeling and improve ones overall sense of well-being. For headaches, a gentle head and neck massage or a cool cloth placed on the forehead may help. A nutritious and balanced diet and nutritional supplements are essential to maintain the health of both the mother and the growing baby. Avoiding caffeine, smoking, and foods rich in refined sugar can also help reduce the severity of symptoms. Smaller, more frequent meals can also help maintain blood-sugar levels. Low blood-sugar levels can result in fatigue, headaches, and irritability.

Between 10 and 20 percent of all pregnant women suffer from depression. Pregnant women, particularly those who have had a previous complicated pregnancy or miscarriage, may also suffer from anxiety. The support of family and friends can be critical for such women, and some women respond well to psychotherapy. If symptoms are very severe, anti-depressant drugs are available that are safe to take during pregnancy.